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Sridhar BHAVANI, David P. HODSON, Julio HUERTA-ESPINO, Mandeep S. RANDHAWA, Ravi P. SINGH
《农业科学与工程前沿（英文）》 2019年 第6卷 第3期 页码 210-224 doi: 10.15302/J-FASE-2019268
Races belonging to the Ug99 (TTKSK) lineage of the wheat stem rust fungus, carrying complex virulence combinations, and their migration to countries in Africa, Middle East and Asia continue to pose a significant threat to global wheat production. The rapid spread of additional races, e.g., TKTTF or the Digalu lineage, in several countries causing localized epidemics reminds us of the vulnerability of wheat germplasm to stem rust disease, a formidable foe referenced as early as biblical times. A global rust monitoring system reflecting increased surveillance efforts has identified 13 races within the Ug99 lineage in 13 countries and unrelated lineages are emerging, spreading and posing serious threats to wheat production. Race TKTTF has caused localized epidemics in Ethiopia and its variants have been recently implicated in stem rust outbreaks in Europe. Concerted research efforts have resulted in the identification of several new resistance (APR) genes and gene combinations for use in breeding. Combining multiple adult plant resistance genes in high-yielding backgrounds and discovery of new quantitative trait loci conferring stem rust resistance has progressed in the recent years, enhancing the durability of resistance. Effective gene stewardship and new generation breeding materials and cultivars that combine multiple race-specific or minor to intermediate effect APR genes, complemented by active surveillance and monitoring, have helped to limit major epidemics and increase grain yield potential in key target environments.
关键词： adult plant resistance black rust race-specific resistance Triticum aestivum
Menglu Zhang, Sheng Chen, Xin Yu, Peter Vikesland, Amy Pruden
《环境科学与工程前沿（英文）》 2019年 第13卷 第3期 doi: 10.1007/s11783-019-1124-5
Extracellular DNA structure damaged by chlorination was characterized. Integrity of extracellular ARG genetic information after chlorination was determined. Typical chlorine doses will likely effectively diminish extracellular DNA and ARGs. Plasmid DNA/ARGs were less readily broken down than genomic DNA. The Bioanalyzer methodology effectively documented damage incurred to DNA.
关键词： Antibiotic resistance Antibiotic resistance genes (ARGs) Extracellular DNA/ARGs Chlorination
Breeding for pre-harvest sprouting resistance in bread wheat under rainfed conditions
Muhammad ZEESHAN, Waheed ARSHAD, Muhammad Imran KHAN, Shiraz ALI, Ali NAWAZ, Amina BATOOL, Muhammad TARIQ, Muhammad Imran AKRAM, Muhammad Amjad ALI
《农业科学与工程前沿（英文）》 2018年 第5卷 第2期 页码 253-261 doi: 10.15302/J-FASE-2018218
关键词： bread wheat germination index general combining ability pre-harvest sprouting specific combining ability
Yisheng ZHANG, Delan ZHU
《农业科学与工程前沿（英文）》 2017年 第4卷 第2期 页码 165-171 doi: 10.15302/J-FASE-2017145
关键词： application intensity damage floriculture flowers specific power sprinkler irrigation
《环境科学与工程前沿（英文）》 2021年 第15卷 第6期 doi: 10.1007/s11783-021-1411-9
• Actual SAORs was determined using MLVSS and temperature.
关键词： Specific ammonia oxidation rate Sequencing batch reactor Biomass Temperature coefficient Model simulation
高攀,邹翀
《中国工程科学》 2013年 第15卷 第12期 页码 73-79
拟建的渤海海峡隧道采用隧道掘进机（TBM）施工极具挑战性，其中关键之一就是TBM的掘进速率预测问题。本文将渤海海峡隧道和澳大利亚Clem Jones 隧道进行工程类比，并介绍了比能法在Clem Jones 隧道的应用情况。在Clem Jones 隧道施工过程中，相关研究人员运用比能法对TBM的可掘性进行了分析及预测，从后期的掘进情况来看比能法的预测结果与实际施工吻合得较好。本文在Clem Jones 隧道和渤海海峡隧道对比分析的基础上，认为运用比能法预测TBM的可掘性同样适用于渤海海峡隧道的TBM施工。
Prevalence of antifolate drug resistance markers in in China
《医学前沿（英文）》 2022年 第16卷 第1期 页码 83-92 doi: 10.1007/s11684-021-0894-x
关键词： drug resistance antifolates molecular markers Plasmodium vivax China
Metagenomic analysis on resistance genes in water and microplastics from a mariculture system
《环境科学与工程前沿（英文）》 2022年 第16卷 第1期 页码 4-4 doi: 10.1007/s11783-021-1438-y
Microplastics existing widely in different matrices have been regarded as a reservoir for emerging contaminants. Mariculture systems have been observed to host microplastics and antibiotic resistance genes (ARGs). However, more information on proliferation of ARGs and metal resistance genes (MRGs) in mariculture system at the presence of microplastics is needed.
关键词： Antibiotic resistance genes Metal resistance genes Metagenomic analysis Microplastics Mariculture
An integrated approach to site-specific management zone delineation
Yuxin MIAO, David J. MULLA, Pierre C. ROBERT
《农业科学与工程前沿（英文）》 2018年 第5卷 第4期 页码 432-441 doi: 10.15302/J-FASE-2018230
Dividing fields into a few relatively homogeneous management zones (MZ) is a practical and cost-effective approach to precision agriculture. There are three basic approaches to MZ delineation using soil and/or landscape properties, yield information, and both sources of information. The objective of this study is to propose an integrated approach to delineating site-specific MZ using relative elevation, organic matter, slope, electrical conductivity, yield spatial trend map, and yield temporal stability map (ROSE-YSTTS) and evaluate it against two other approaches using only soil and landscape information (ROSE) or clustering multiple year yield maps (CMYYM). The study was carried out on two no-till corn-soybean rotation fields in eastern Illinois, USA. Two years of nitrogen (N) rate experiments were conducted in Field B to evaluate the delineated MZs for site-specific N management. It was found that in general the ROSE approach was least effective in accounting for crop yield variability (8.0%–9.8%), while the CMYYM approach was least effective in accounting for soil and landscape (8.9%–38.1%), and soil nutrient and pH variability (9.4%–14.5%). The integrated ROSE-YSTTS approach was reasonably effective in accounting for the three sources of variability (38.6%–48.9%, 16.1%–17.3% and 13.2%–18.7% for soil and landscape, nutrient and pH, and yield variability, respectively), being either the best or second best approach. It was also found that the ROSE-YSTTS approach was effective in defining zones with high, medium and low economically optimum N rates. It is concluded that the integrated ROSE-YSTTS approach combining soil, landscape and yield spatial-temporal variability information can overcome the weaknesses of approaches using only soil, landscape or yield information, and is more robust for MZ delineation. It also has the potential for site-specific N management for improved economic returns. More studies are needed to further evaluate their appropriateness for precision N and crop management.
关键词： economically optimum nitrogen rate fuzzy cluster analysis precision nitrogen management site-specific management soil landscape property yield map
Taking advantage of drug resistance, a new approach in the war on cancer
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《医学前沿（英文）》 2018年 第12卷 第4期 页码 490-495 doi: 10.1007/s11684-018-0647-7
Identification of the driver mutations in cancer has resulted in the development of a new category of molecularly targeted anti-cancer drugs. However, as was the case with conventional chemotherapies, the effectiveness of these drugs is limited by the emergence of drug-resistant variants. While most cancer therapies are given in combinations that are designed to avoid drug resistance, we discuss here therapeutic approaches that take advantage of the changes in cancer cells that arise upon development of drug resistance. This approach is based on notion that drug resistance comes at a fitness cost to the cancer cell that can be exploited for therapeutic benefit. We discuss the development of sequential drug therapies in which the first therapy is not given with curative intent, but to induce a major new sensitivity that can be targeted with a second drug that selectively targets the acquired vulnerability. This concept of collateral sensitivity has hitherto not been used on a large scale in the clinic and holds great promise for future cancer therapy.
关键词： cancer drug resistance genetic screens senescence targeted therapy
Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors
《医学前沿（英文）》 2022年 第16卷 第5期 页码 701-713 doi: 10.1007/s11684-022-0951-0
关键词： acquired resistance EGFR inhibitor apoptosis lung cancer
Transmission of antibiotic resistance genes in agroecosystems: an overview
Jizheng HE, Zhenzhen YAN, Qinglin CHEN
《农业科学与工程前沿（英文）》 2020年 第7卷 第3期 页码 329-332 doi: 10.15302/J-FASE-2020333
The use of antibiotics in human medicine and animal husbandry has resulted in the continuous release of antibiotics into the environment, which imposes high selection pressure on bacteria to develop antibiotic resistance. The spread and aggregation of antibiotic resistance genes (ARGs) in multidrug-resistant pathogens is one of the most intractable clinical challenges. Numerous studies have been conducted to profile the patterns of ARGs in agricultural ecosystems, as this is closely related to human health and wellbeing. This paper provides an overview of the transmission of ARGs in agricultural ecosystems resulting from the application of animal manures and other organic amendments. The future need to control and mitigate the spread of antibiotic resistance in agricultural ecosystems is also discussed, particularly from a holistic perspective, and requires multiple sector efforts to translate fundamental knowledge into effective strategies.
关键词： agroecosystem antibiotic resistance public health soil-plant system
Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic
《环境科学与工程前沿（英文）》 2022年 第16卷 第9期 doi: 10.1007/s11783-022-1548-1
• Water-dispersible nano-pollutions exhibit type-specific toxic effects on E. coli.
关键词： Nano-toxicity Nano-plastics Quantum dots Microbial metabolite Metabolic dysregulation
《环境科学与工程前沿（英文）》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1342-x
• SMX addition had negative effect on acetoclastic methanogens in mesophilic AD.
关键词： Pig manure Antibiotics Anaerobic digestion Resistance genes Microbial community
River restoration challenges with a specific view on hydromorphology
Jianhua LI, Stephan HOERBINGER, Clemens WEISSTEINER, Lingmin PENG, Hans Peter RAUCH
《结构与土木工程前沿（英文）》 2020年 第14卷 第5期 页码 1033-1038 doi: 10.1007/s11709-020-0665-9
标题 作者 时间 类型 操作
Progress in breeding for resistance to Ug99 and other races of the stem rust fungus in CIMMYT wheat germplasm
Sridhar BHAVANI, David P. HODSON, Julio HUERTA-ESPINO, Mandeep S. RANDHAWA, Ravi P. SINGH
期刊论文
Degradation of extracellular genomic, plasmid DNA and specific antibiotic resistance genes by chlorination
Menglu Zhang, Sheng Chen, Xin Yu, Peter Vikesland, Amy Pruden
期刊论文
Breeding for pre-harvest sprouting resistance in bread wheat under rainfed conditions
Muhammad ZEESHAN, Waheed ARSHAD, Muhammad Imran KHAN, Shiraz ALI, Ali NAWAZ, Amina BATOOL, Muhammad TARIQ, Muhammad Imran AKRAM, Muhammad Amjad ALI
期刊论文
Influence of sprinkler irrigation droplet diameter, application intensity and specific power on flower
Yisheng ZHANG, Delan ZHU
期刊论文
The combined effects of biomass and temperature on maximum specific ammonia oxidation rate in domestic
期刊论文
An integrated approach to site-specific management zone delineation
Yuxin MIAO, David J. MULLA, Pierre C. ROBERT
期刊论文
Transmission of antibiotic resistance genes in agroecosystems: an overview
Jizheng HE, Zhenzhen YAN, Qinglin CHEN
期刊论文
Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic
期刊论文
swine manure with sulfamethoxazole and norfloxacin: Dynamics of microbial communities and evolution of resistance
期刊论文
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